The European Myeloma Network (EMN)

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EHA-13 Scientific Working Group “Multiple Myeloma”

SWG Multiple Myeloma conducted a scientific meeting chaired by Pieter Sonneveld (Rotterdam, the Netherlands) and Hans E. Johnsen (Aalborg, Denmark). 35 attendants participated. The focus of the meeting was “The Myeloma Stem Cell” .

Hans E. Johnsen introduced the concept and the scientific background of the myeloma stem cell. Martin Perez Andres (Salamanca, Spain) addressed the B cell hierarchy in B cell malignancies and myeloma. Various B-cell compartments that may carry early clonal characteristics were defined.

Surinder Sahota (Southampton, United Kingdom) described molecular approaches to track the myeloma compartment and identify distinct profiles for pre-plasma cells that may belong to the myeloma clone. Pieter Sonneveld presented gene expression data of myeloma patients, and introduced the concept of a molecular profile of chemo-resistance of myeloma stem cells.

Finally, Karin Vanderkerken (Brussels, Belgium) presented data of the 5TMM myeloma mouse model, which serves as a realistic pre-clinical model for myeloma (stem-) cell analysis.

27 Oct 2008 by kirsten

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News Archives

All published news can be found in the news archives.

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WP1: Homepage

WP2: Clinical data registration

WP3: Tissue banks

WP4: Clinical network

WP5: Normal cell counterpart

WP6: Genetics and proteomics

WP7: Proliferation and apaptosis